ER Stress Proteins in Autoimmune and Inflammatory Diseases

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ER Stress Proteins in Autoimmune and Inflammatory Diseases

Over the past two decades, heat shock proteins (HSPs) have been implicated in inflammatory responses and autoimmunity. HSPs were originally believed to maintain protein quality control in the cytosol. However, they also exist extracellularly and appear to act as inflammatory factors. Recently, a growing body of evidence suggested that the other class of stress proteins such as, endoplasmic reti...

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ژورنال

عنوان ژورنال: Frontiers in Immunology

سال: 2012

ISSN: 1664-3224

DOI: 10.3389/fimmu.2012.00048